Top Biotechnology companies in United States by Operating Income Margin

This ranking features the top 472 Biotechnology companies in United States ranked by Operating Income Margin, averaging a Operating Income Margin of -4,264,743.57%, for January 15, 2025.

United States

Biotechnology

#	Name	Operating Income Margin	Reported Date	Stock Price	Change	Country
1	Summit Therapeutics Inc. 1 SMMT	198,753.95%	Sept. 30, 2023	USD 16.65	-8.42%	United States
2	Royalty Pharma plc 2 RPRX	68.14%	Sept. 30, 2024	USD 30.03	0.13%	United States
3	SIGA Technologies, Inc. 3 SIGA	60.19%	Sept. 30, 2024	USD 6.33	4.46%	United States
4	Halozyme Therapeutics, Inc. 4 HALO	50.35%	Sept. 30, 2024	USD 53.83	-0.57%	United States
5	United Therapeutics Corporation 5 UTHR	46.42%	Sept. 30, 2024	USD 364.70	0.50%	United States
6	Protagonist Therapeutics, Inc. 6 PTGX	46.05%	Sept. 30, 2024	USD 36.67	-1.26%	United States
7	Catalyst Pharmaceuticals, Inc. 7 CPRX	37.78%	Sept. 30, 2024	USD 22.19	-0.09%	United States
8	Zoetis Inc. 8 ZTS	36.45%	Sept. 30, 2024	USD 164.41	-1.15%	United States
9	Lantheus Holdings, Inc. 9 LNTH	31.68%	Sept. 30, 2024	USD 92.62	-2.15%	United States
10	Sotera Health Company 10 SHC	31.23%	Sept. 30, 2024	USD 12.76	-2.52%	United States
11	ADMA Biologics, Inc. 11 ADMA	30.01%	Sept. 30, 2024	USD 16.32	-1.03%	United States
12	Amphastar Pharmaceuticals, Inc. 12 AMPH	29.71%	Sept. 30, 2024	USD 38.48	1.48%	United States
13	Gilead Sciences, Inc. 13 GILD	29.63%	Sept. 30, 2024	USD 91.00	1.18%	United States
14	Regeneron Pharmaceuticals, Inc. 14 REGN	28.92%	Sept. 30, 2024	USD 690.87	-3.63%	United States
15	Ironwood Pharmaceuticals, Inc. 15 IRWD	28.68%	Sept. 30, 2024	USD 3.65	-3.18%	United States
16	Entrada Therapeutics, Inc. 16 TRDA	26.85%	Sept. 30, 2024	USD 12.49	-6.58%	United States
17	Harmony Biosciences Holdings, Inc. 17 HRMY	25.71%	Sept. 30, 2024	USD 36.42	-0.08%	United States
18	Illumina, Inc. 18 ILMN	25.26%	Sept. 29, 2024	USD 136.48	-5.37%	United States
19	Exelixis, Inc. 19 EXEL	25.16%	Sept. 27, 2024	USD 35.65	0.99%	United States
20	AbbVie Inc. 20 ABBV	24.89%	Sept. 30, 2024	USD 175.55	-0.67%	United States
21	Agilent Technologies, Inc. 21 A	23.10%	Oct. 31, 2024	USD 143.43	1.04%	United States
22	Corcept Therapeutics Incorporated 22 CORT	22.81%	Sept. 30, 2024	USD 51.66	1.18%	United States
23	MEI Pharma, Inc. 23 MEIP	22.27%	June 30, 2024	USD 2.75	1.10%	United States
24	MiMedx Group, Inc. 24 MDXG	21.81%	Sept. 30, 2024	USD 8.61	0.58%	United States
25	Bristol-Myers Squibb Company 25 BMY	21.74%	Sept. 30, 2024	USD 55.74	0.69%	United States
26	Biogen Inc. 26 BIIB	21.11%	Sept. 30, 2024	USD 143.06	-4.74%	United States
27	Balchem Corporation 27 BCPC	20.78%	Sept. 30, 2024	USD 158.62	1.47%	United States
28	MannKind Corporation 28 MNKD	20.51%	Sept. 30, 2024	USD 6.03	-1.63%	United States
29	Stryker Corporation 29 SYK	20.37%	Sept. 30, 2024	USD 362.80	0.50%	United States
30	biote Corp. 30 BTMD	20.16%	Sept. 30, 2024	USD 5.67	2.35%	United States
31	Danaher Corporation 31 DHR	19.87%	Sept. 27, 2024	USD 237.62	-0.94%	United States
32	Bio-Techne Corporation 32 TECH	19.54%	Sept. 30, 2024	USD 74.73	-2.21%	United States
33	Amgen Inc. 33 AMGN	18.85%	Sept. 30, 2024	USD 267.10	-1.14%	United States
34	Thermo Fisher Scientific Inc. 34 TMO	16.92%	Sept. 28, 2024	USD 556.99	0.27%	United States
35	Pfizer Inc. 35 PFE	16.85%	Sept. 29, 2024	USD 26.41	-1.46%	United States
36	Krystal Biotech, Inc. 36 KRYS	16.54%	Sept. 30, 2024	USD 142.64	-5.10%	United States
37	DexCom, Inc. 37 DXCM	15.88%	Sept. 30, 2024	USD 79.17	-0.84%	United States
38	IQVIA Holdings Inc. 38 IQV	14.20%	Sept. 30, 2024	USD 197.96	-3.26%	United States
39	Charles River Laboratories International, Inc. 39 CRL	13.86%	Sept. 28, 2024	USD 178.08	-6.34%	United States
40	Puma Biotechnology, Inc. 40 PBYI	13.30%	Sept. 30, 2024	USD 3.09	0.33%	United States
41	Bio-Rad Laboratories, Inc. 41 BIO	12.19%	Sept. 30, 2024	USD 342.23	-2.69%	United States
42	ACADIA Pharmaceuticals Inc. 42 ACAD	12.08%	Sept. 30, 2024	USD 16.90	-5.59%	United States
43	Corteva, Inc. 43 CTVA	11.80%	Sept. 30, 2024	USD 60.89	1.60%	United States
44	Revvity, Inc. 44 RVTY	11.79%	Sept. 29, 2024	USD 120.73	-1.61%	United States
45	BioMarin Pharmaceutical Inc. 45 BMRN	11.40%	Sept. 30, 2024	USD 63.81	-4.75%	United States
46	Artivion, Inc. 46 AORT	10.69%	Sept. 30, 2024	USD 29.68	1.16%	United States
47	Bruker Corporation 47 BRKR	10.13%	Sept. 30, 2024	USD 61.26	-2.69%	United States
48	Avantor, Inc. 48 AVTR	9.72%	Sept. 30, 2024	USD 21.72	-1.36%	United States
49	Laboratory Corporation of America Holdings 49 LH	8.80%	Sept. 30, 2024	USD 234.50	0.17%	United States
50	TransMedics Group, Inc. 50 TMDX	7.84%	Sept. 30, 2024	USD 62.54	-2.36%	United States

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Frequently Asked Questions

Which Biotechnology company in United States has the highest Operating Income Margin ?

The Biotechnology company in United States with the highest Operating Income Margin is Summit Therapeutics Inc. (NasdaqGM: SMMT) at 198,753.95%.
Which Biotechnology company in United States has the lowest Operating Income Margin ?

The Biotechnology company in United States with the lowest Operating Income Margin is Inhibikase Therapeutics, Inc. (NasdaqCM: IKT) at -2,006,394,100.00%.

What are the top 10 Biotechnology companies in United States by Operating Income Margin ?

The top 10 Biotechnology companies in United States by Operating Income Margin are Summit Therapeutics Inc., Royalty Pharma plc, SIGA Technologies, Inc., Halozyme Therapeutics, Inc., United Therapeutics Corporation, Protagonist Therapeutics, Inc., Catalyst Pharmaceuticals, Inc., Zoetis Inc., Lantheus Holdings, Inc. and Sotera Health Company.
What are the bottom 10 Biotechnology companies in United States by Operating Income Margin ?

The bottom 10 Biotechnology companies in United States by Operating Income Margin are Inhibikase Therapeutics, Inc., Allogene Therapeutics, Inc., Forte Biosciences, Inc., Immix Biopharma, Inc., Bullfrog AI Holdings, Inc. Common Stock, Benitec Biopharma Inc., Cadrenal Therapeutics, Inc. Common Stock, Acelyrin, Inc., Greenwich LifeSciences, Inc. and Altimmune, Inc..