Day One Biopharmaceuticals Inc Return on Equity (ROE) 1 year YoY Change (%) is -285.49% for the quarter ending March 31, 2024, a -238.54% change year over year. Return on equity (ROE) measures the profitability of a company relative to its shareholders' equity. It is calculated by dividing the net income by the shareholders' equity. This ratio indicates the return generated for each unit of shareholders' equity invested in the company. A higher ROE suggests better profitability and value creation for shareholders. The measure "Change (%)" refers to the percentage change in the value of a financial metric between two time points. This measure provides a relative perspective on the magnitude of change.